Provided here are replaced by aromatic compounds that are inhibitors of tRNA synthetase, and therefore can be used as antimicrobial agents. Connections described herein may be used to treat or prevent a condition caused by or contributed to its gram-positive, gram negative, anaerobic bacteria and fungal organisms, especially against bacteria such strattera 10mg as staphylococci, enterococci, streptococci, Haemophilus influenzae, Moraxalla, coli, Chlamydia , Mycoplasm, Legionella, Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillus or fungal organisms Enterobactericeae and, for example, Aspergillus, Blastomyces, Candida, Coccidiodes, Cryptococcus, Epidermophyton, Hendersonula, Histoplasma, Microsporum, Paecilomyces, Paracoccidiodes, pneumonia, Trichophyton, or Trichosporium. Methods of obtaining these compounds, their pharmaceutical compositions and methods for treatment of microbial infections are also provided. .
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